[PDF] from uccs.eduA Cerutti - Annual Review of Immunology, 2011 - annualreviews.org Mucosal surfaces are colonized by large communities of commensal bacteria and represent the primary site of entry for pathogenic agents. To prevent microbial intrusion, mucosal B cells release large amounts of immunoglobulin (Ig) molecules through multiple follicular and ... Cited by 2 - Related articles - All 3 versions
S Pruzina, GT Williams, G Kaneva… - Protein Engineering …, 2011 - Oxford Univ Press Mice carrying human immunoglobulin transloci were immunised with HIV-1 gp140 antigen to gain insight into the range and nature of human monoclonal antibodies (mAbs) that can be elicited from such humanised mice. Using five-feature mice that harbour YAC-based germline- ...
A Plückthun, A Honegger… - US Patent …, 2011 - freepatentsonline.com 22. A nucleic acid molecule encoding a stabilized chimeric immunoglobulin or immunoglobulin fragment (chimera) that comprises i) VH domain antigen-binding loops from a donor immunoglobulin or immunoglobulin fragment (donor) which is able to bind to an antigen, and ii) VH ... Related articles - Cached - All 2 versions
X Ren, R Siegel, U Kim… - Molecular Cell, 2011 - Elsevier B cell-specific coactivator OCA-B, together with Oct-1/2, binds to octamer sites in promoters and enhancers to activate transcription of immunoglobulin (Ig) genes, although the mechanisms underlying their roles in enhancer-promoter communication are unknown. Here, we demonstrate a ... All 2 versions
Y He… - … of the National Academy of Sciences, 2011 - National Acad Sciences Edited by Jeffrey V. Ravetch, The Rockefeller University, New York, NY, and approved June 20, 2011 (received for review May 2, 2011) Fc receptors transport maternal antibodies across epithelial cell barriers to passively immunize newborns. FcRY, the functional counterpart ...