[PDF] from nyu.eduMT Pallotta, C Orabona, C Volpi, C Vacca… - Nature …, 2011 - nature.com Regulation of tryptophan metabolism by indoleamine 2,3-dioxygenase (IDO) in dendritic cells (DCs) is a highly versatile modulator of immunity. In inflammation, interferon-γ is the main inducer of IDO for the prevention of hyperinflammatory responses, yet IDO is also responsible for ...
HL Weiner, AP da Cunha… - Immunological …, 2011 - Wiley Online Library Summary: The gut-associated lymphoid tissue is the largest immune organ in the body and is the primary route by which we are exposed to antigens. Tolerance induction is the default immune pathway in the gut, and the type of tolerance induced relates to the dose of antigen fed: ... Cited by 5 - Related articles - All 3 versions
JA Philips… - Cell, 2011 - Elsevier In the context of tuberculosis (TB), directly observed therapy involves a trained observer watching patients take their TB medications in order to improve adherence and achieve a cure. In this issue of Cell, Adams and Takaki and colleagues (Adams et al., 2011) bring new meaning ... All 2 versions
P Matzinger… - Nature Reviews Immunology, 2011 - nature.com In this Essay, we offer a new perspective on how immune responses are regulated. We do not cover how they are turned on and off, but focus instead on the second major aspect of an immune response: the control of effector class. Although it is generally thought that the class of an ... Cited by 2 - Related articles - All 3 versions
M Papatriantafyllou - Nature Reviews Immunology, 2011 - nature.com Natural CD4 + regulatory T (T Reg ) cells arise in the thymus following ligation of high-affinity T cell receptors (TCRs), whereas induced T Reg cells are generated in the periphery following CD4 + T cell activation in the presence of immunosuppressive cytokines or other ...
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