CE Inturrisi… - The Opiate Receptors, 2011 - Springer ... 441 16 Molecular Modulation of In Vivo Tolerance adaptation known as pharmacodynamic tolerance. Tolerance to opioids is predominantly of the pharmacodynamic type. ... Opioid tolerance is predominantly of the pharmacological nonassociative and pharmacodynamic type. ... Related articles - All 2 versions
M White-Koning, E Civade, B Geoerger… - Clinical Cancer …, 2011 - AACR ... Analysis of Erlotinib in Adults and Children Reveals Pharmacokinetic Characteristics as the Main Factor Explaining Tolerance Particularities in ... Purpose: The aim of this pharmacokinetic– pharmacodynamic (PK–PD) analysis was to evaluate the pharmacologic characteristics of ... Related articles - All 2 versions
GB Parker, HL Brotchie… - International clinical …, 2011 - journals.lww.com ... pharmacokinetic tolerance' (where alterations in absorption, distribution, biotransformation or drug elimination lead to a reduced concentration of the drug acting at its target site as a consequence of earlier or ongoing exposure) and 'pharmacodynamictolerance', where there ... Cited by 1 - Related articles - All 5 versions
[PDF] from mdpi.comS Sussman, A Leventhal, RN Bluthenthal… - International Journal of …, 2011 - mdpi.com ... has broadened in scope from referring to only physiologic processes related to drug misuse (pharmacodynamictolerance and withdrawal) to a more elaborate biopsychosocial syndrome with commonalities across several behaviors. ...
[PDF] from benthamscience.comA O'Sullivan… - Open Addiction Journal, 2011 - benthamscience.com ... in mood reactions to MDMA [3-5], and the adverse mood states afterwards [6]. The universal decline in positive ratings with repeated Ecstasy, was consistent with previous reports of decline in efficacy [7], and is consistent with chronic pharmacodynamictolerance [8]. The only ... Related articles - View as HTML