B Rooney, H O'Donovan, A Gaffney, M Browne… - FEBS letters, 2011 - Elsevier We describe the activation of Wnt signalling in mesangial cells by CCN2. CCN2 stimulates phosphorylation of LRP6 and GSK-3β resulting in accumulation and nuclear localisation of β-catenin, TCF/LEF activity and expression of Wnt targets. This is coincident with decreased phosphorylation ... Cited by 3 - Related articles - All 3 versions
A Lu, M Miao, TR Schoeb, A Agarwal… - The American Journal of …, 2011 - Elsevier Transforming growth factor-β (TGF-β) is key in the pathogenesis of diabetic nephropathy. Thrombospondin 1 (TSP1) expression is increased in diabetes, and TSP1 regulates latent TGF-β activation in vitro and in diabetic animal models. Herein, we investigate the effect of blockade of TSP1- ... Related articles - All 4 versions
G Viswanathan, H Tighiouart… - American Journal of …, 2011 - urologyaccess.org « PreviousNext »American Journal of Kidney Diseases Volume 57, Issue 4 , Page B102, April 2011. 341 Complications of Chronic Kidney Disease (CKD) by Level of Albuminuria and Proteinuria in the Irbesartan in DiabeticNephropathy Trial (IDNT). Gautham Viswanathan*: ... Cached - All 2 versions
[HTML] from pnas.orgCH Wang, F Li, S Hiller, HS Kim… - Proceedings of the …, 2011 - National Acad Sciences Polymorphisms in the human endothelial nitric oxide synthase (eNOS) gene (NOS3) have been associated with advanced nephropathy in diabetic patients and with decreased expression in tissue culture. However, direct proof that modest genetic decreases in eNOS expression ... Related articles - All 4 versions
[HTML] from nih.govK Inoki, H Mori, J Wang, T Suzuki… - The Journal of clinical …, 2011 - ncbi.nlm.nih.gov 1 Life Sciences Institute, 2 Department of Molecular and Integrative Physiology, and 3 Division of Nephrology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA. 4 Biozentrum, University of Basel, Basel, Switzerland. 5 Translational ... Cited by 3 - Related articles - All 4 versions
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