L Gardner, Y Zou, A Mara, TA Cropp… - Mol. BioSyst., 2011 - xlink.rsc.org Bacterial cells control resistance to the macrolide antibiotic erythromycin using the MphR(A) repressor protein. Erythromycin binds to MphR(A), causing release of the PmphR promoter, activating expression of the 2′-phosphotransferase Mph(A). We engineered the MphR(A)/promoter ...
JH Jorgensen, ML McElmeel… - Journal of Clinical …, 2011 - Am Soc Microbiol Department of Pathology, University of Texas Health Science Center, San Antonio, TX,1 10 Respiratory Diseases Branch, Centers for Disease Control and Prevention, Atlanta, GA,2 11 Department of Pathology, University of Iowa, Iowa City, IA,3 Microbiology Laboroatry, 12 ... All 2 versions
[PDF] from illinois.eduEM Stang… - Angewandte Chemie International …, 2011 - Wiley Online Library The erythromycins, discovered and isolated in the early 1950s, are the best-known members of the clinically important macrolide class of antibiotics.1 The 14-membered macrolactone core imbedded in these natural products has inspired new synthetic methods for the ... All 5 versions
RM Franke, CS Lancaster, CJ Peer… - Clinical Pharmacology …, 2011 - nature.com The macrolide antiobiotic erythromycin undergoes extensive hepatic metabolism and is commonly used as a probe for cytochrome P450 (CYP) 3A4 activity. By means of a transporter screen, erythromycin was identified as a substrate for the transporter ABCC2 (MRP2) and its murine ortholog, ... Cited by 1 - Related articles - All 3 versions
[HTML] from annemergmed.comD Pateron, E Vicaut, E Debuc, K Sahraoui… - Annals of Emergency …, 2011 - Elsevier Two hundred fifty-three patients (181 men, mean age 61 years [SD 15 years], 84 with cirrhosis) were randomized: 84 (erythromycin group), 85 (nasogastric group), and 84 (nasogastric-erythromycin group). Overall, there was 85% satisfactory stomach ... Cited by 2 - Related articles - All 3 versions
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